Staff: Prof. Juergen Haas MD, Dr. Samantha Griffiths
The objective of the research programme of the Haas group at the University of Edinburgh is the identification and characterisation of key steps in the FMDV life cycle using state-of-art genomic technologies such as genome-scale RNA interference and yeast-two-hybrid protein interaction screens. The identification of viral and host factors that are crucial for the extremely fast viral replication, the establishment of latency in some affected animals and the viral pathogenesis will help to develop new approaches for prevention and therapy.
Friedel, C and Haas, J. (2011) Virus-host interactomes and global models of virus-infected cells. Trends Microbiol. 19:501-508.